Job i Storkøbenhavn
Do you want to contribute to building our process modelling function in R&D and set your mark on how we optimize production processes for the future? Then you could be our new Process Systems Engineer for design and optimization.
About the department
The job is placed in CMC API Development, R&D, located in Bagsværd. Our main responsibility is to develop manufacturing processes for new proteins and peptides in close collaboration with the research and manufacturing units (clinical and market). In CMC API Development we are increasing our focus on improving emerging processes by application of flow sheet models (Digital Twins). The Digital Twin combines a model for a facility with a process model and enables us to optimize for different objectives throughout the project lifecycle, including capacity, facility fit, and process economy. The Digital Twin is based on a dynamic mass balance for the entire system and production scenarios are simulated by solving the system of equations using Discrete Event Simulation. For selected process steps mechanistic models are included to increase model fidelity. Our aim for the future is to enable more qualified and timely decisions on process design such as batch vs continuous operation, solvent prep strategy, and recycle options.
You will be part of a small team, CMC Bioprocess Improvement-Optimization (CMC BIO), which is dedicated to model ba...